The comparators in the PIONEER program were placebo PIONEER 1, 4, 5, 6, and 8, empagliflozin 25 mg PIONEER 2, sitagliptin 100 mg PIONEER 3 and 7, liraglutide 1 <a href=https://enhanceyourlife.mom/>60mg priligy</a> It is indicated in combination with fulvestrant as initial endocrine based therapy or following disease progression on endocrine therapy