If these observations are independently confirmed, lack of ESR1 mutation could then be used to select those patients who would be treated with exemestane alone before moving on to fulvestrant, much as KRAS wild type status is required for clinical benefit from anti epidermal growth factor receptor antibody therapy in colon cancer <a href=https://cialis.lat/discover-the-best-prices-for-cialis>generic 5mg cialis best price</a>
